Crash Course Pharmacology ebook free download

 

Crash Course Pharmacology ebook free download

Crash Course Pharmacology ebook free download

Crash Course Pharmacology ebook free download

Crash Course Pharmacology ebook free download

Preface

This book aims to explain both the theory and clinical application of pharmacology. It is easily accessible and can be used to support learning and aid revision. The introductory chapter gives a comprehensive overview of the basic concepts of pharmacology. The following chapters then elaborate on these concepts, focusing on specific systems within the body. This new edition is clear and concise, featuring clinical vignettes and illustrations throughout. New material regarding recent pharmacological advances has been included. The self-assessment section has been updated to reflect current testing strategies, now featuring a ‘Best of fives’ section. I hope you find the book informative and enjoyable, and wish you luck in learning the fascinating subject of pharmacology.

Contents

1. Introduction to pharmacology . . . . . . . 1
Molecular basis of pharmacology . . . . . . 1
Drug-receptor interactions . . . . . . . . . 6
Pharmacokinetics . . . . . . . . . . . . . 8
Drug interactions and adverse effects . . . 14
Drug history and drug development. . . . 16
2. Cardiovascular system . . . . . . . . . . 19
The heart . . . . . . . . . . . . . . . . 19
The circulation . . . . . . . . . . . . . . 29
Haemostasis and thrombosis . . . . . . . 38
The blood and fluid replacement . . . . . 43
3. Respiratory system . . . . . . . . . . . 45
Basic concepts . . . . . . . . . . . . . . 45
Obstructive airways diseases . . . . . . . 46
Respiratory stimulants and pulmonary
surfactants . . . . . . . . . . . . . . . 51
Antitussives and mucolytics . . . . . . . . 51
4. Peripheral nervous system . . . . . . . . 53
Nerve conduction . . . . . . . . . . . . 53
Somatic nervous system . . . . . . . . . 54
Autonomic nervous system . . . . . . . . 58
Nitrergic nervous system . . . . . . . . . 66
5. Central nervous system . . . . . . . . . 69
Basic concepts . . . . . . . . . . . . . . 69
Parkinson’s disease and parkinsonism . . . 69
Dementia . . . . . . . . . . . . . . . . 73
Anxiety and sleep disorders . . . . . . . . 74
Sleep disorders and hypnotics. . . . . . . 74
Affective disorders . . . . . . . . . . . . 77
Psychotic disorders . . . . . . . . . . . . 81
Drug misuse . . . . . . . . . . . . . . . 86
Epilepsy . . . . . . . . . . . . . . . . . 90
The eye. . . . . . . . . . . . . . . . . 95
6. Endocrine and reproductive systems . . . 99
The thyroid gland . . . . . . . . . . . . 99
The endocrine pancreas and
diabetes mellitus . . . . . . . . . . . . 102
Adrenal corticosteroids . . . . . . . . . . 107
The reproductive system . . . . . . . . . 112
Bone and calcium . . . . . . . . . . . . 117
7. Kidney and urinary system . . . . . . . . 119
Basic concepts . . . . . . . . . . . . . . 119
The kidney . . . . . . . . . . . . . . . 119
Diuretics . . . . . . . . . . . . . . . . 121
The urinary system. . . . . . . . . . . . 124
8. Gastrointestinal system . . . . . . . . . 127
The stomach . . . . . . . . . . . . . . 127
Nausea and vomiting. . . . . . . . . . . 130
The intestines . . . . . . . . . . . . . . 131
The pancreas and gall
bladder . . . . . . . . . . . . . . . . 136
9. Pain and anaesthesia . . . . . . . . . . 137
Basic concepts . . . . . . . . . . . . . . 137
Opioid analgesic drugs . . . . . . . . . . 140
Headache and neuralgic pain . . . . . . . 142
Local anaesthesia . . . . . . . . . . . . 143
General anaesthesia . . . . . . . . . . . 145
10. Inflammation, allergic diseases
and immunosuppression . . . . . . . . . 151
Inflammation . . . . . . . . . . . . . . 151
Inflammatory diseases . . . . . . . . . . 155
Allergic disorders and drug
therapy . . . . . . . . . . . . . . . . 161
Immunosuppressants. . . . . . . . . . . 163
11. Infectious diseases . . . . . . . . . . . 167
Antibacterial drugs . . . . . . . . . . . . 167
Antiviral drugs . . . . . . . . . . . . . . 175
Antifungal drugs . . . . . . . . . . . . . 181
Antiprotozoal drugs . . . . . . . . . . . 183
Anthelmintic drugs. . . . . . . . . . . . 187
12. Cancer . . . . . . . . . . . . . . . . . 191
Concepts of cancer
chemotherapy . . . . . . . . . . . . . 191
Cytotoxic chemotherapy . . . . . . . . . 192
Endocrine therapy . . . . . . . . . . . . 196
Immunotherapy . . . . . . . . . . . . . 197
The future. . . . . . . . . . . . . . . . 197
Self-assessment . . . . . . . . . . . . . . . 199
Best of fives (BOFs) . . . . . . . . . . . . . 201
Extended-matching questions
(EMQs) . . . . . . . . . . . . . . . . . . . 207
BOF answers . . . . . . . . . . . . . . . . 211
EMQ answers . . . . . . . . . . . . . . . . 215
Glossary . . . . . . . . . . . . . . . . . . . 219
Index . . . . . . . . . . . . . . . . . . . . 221

Crash Course Pharmacology ebook free download

Crash Course Pharmacology ebook free download

Crash Course Pharmacology ebook free download

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