Crash Course Pathology ebook free download pdf

 

Crash Course Pathology ebook free download pdf

Crash Course Pathology ebook free download pdf

Crash Course Pathology ebook free download pdf

Crash Course Pathology ebook free download pdf

Preface

 

My ancestor, Prof Rosemary Walker made an astounding showing in controlling this unfathomably extensive short content through a few releases, giving a decent foundation to all parts of pathology and their significance to clinical medication. Mirroring this present Advisor’s unique hobby, the content has been further overhauled and upgraded in a few territories where there is advancement, disarray and unpredictability: pregnancy-related ailments, sickle cell malady, HIV and AIDS, infection, systemic sepsis, and irresistible ailments when all is said in done. The established regions of malignancy and circulatory ailments have likewise been discretely altered to reflect current considering where it makes a difference. On the off chance that every restorative understudy knew the majority of what is in this content, with its proper association of information, instructors could rest all the more effortlessly and the nature of demonstrative critical thinking among youthful specialists would be fundamentally progressed. It will absolutely help you in all parts of your therapeutic course. Exceptional much appreciated and affirmation ought to likewise go to Philip Xiu for his work on the new release.

Contents

Part I: Principles of pathology
1. Introduction to pathology . . . . . . . . . 1
Diseases . . . . . . . . . . . . . . . . . . 1
Pathology . . . . . . . . . . . . . . . . . 1
How pathology is covered in this book . . . 2
2. Inflammation, repair and cell death . . . . . 3
Inflammation . . . . . . . . . . . . . . . 3
Acute inflammation . . . . . . . . . . . . 3
Chemical mediators of inflammation. . . . . 5
Chronic inflammation . . . . . . . . . . . 8
Cell death . . . . . . . . . . . . . . . . 10
3. Cancer . . . . . . . . . . . . . . . . . 15
Definitions and nomenclature . . . . . . . 15
Molecular basis of cancer . . . . . . . . . 18
Tumour growth and spread . . . . . . . . 19
Carcinogenic agents . . . . . . . . . . . 22
Host defences against cancer . . . . . . . 24
Clinical cancer pathology . . . . . . . . . 25
4. Infectious disease . . . . . . . . . . . . 27
General principles of infection. . . . . . . 27
Categories of infectious agent. . . . . . . 28
Mechanisms of pathogenicity . . . . . . . 32
Sepsis . . . . . . . . . . . . . . . . . . 35
Inflammatory responses to infection . . . . 36
Part II: Systemic pathology
5. Pathology of the nervous system . . . . . 37
Disorders of the central nervous system . . 37
Disorders of the peripheral nervous system. 50
Disorders of the autonomic nervous system 53
6. Pathology of the cardiovascular system . . 55
Congenital abnormalities of the heart . . . 55
Atherosclerosis, hypertension and
thrombosis . . . . . . . . . . . . . . . 60
Ischaemic heart disease and heart failure. . 68
Disorders of the heart valves . . . . . . . 72
Diseases of the myocardium . . . . . . . 76
Diseases of the pericardium . . . . . . . . 77
Aneurysms . . . . . . . . . . . . . . . 79
Inflammatory and neoplastic vascular
disease . . . . . . . . . . . . . . . . . 81
Diseases of the veins and lymphatics . . . 84
7. Pathology of the respiratory system. . . . 87
Disorders of the upper respiratory tract . . 87
Disorders of the lungs . . . . . . . . . . 89
Infections of the lungs . . . . . . . . . . 98
Neoplastic diseases of the lungs . . . . . . 104
Diseases of vascular origin . . . . . . . . 108
Diseases of iatrogenic origin . . . . . . . 111
Disorders of the pleura . . . . . . . . . . 111
8. Pathology of the gastrointestinal
system . . . . . . . . . . . . . . . . . 115
Disorders of the upper gastrointestinal
tract . . . . . . . . . . . . . . . . . . 115
Disorders of the stomach . . . . . . . . . 119
General aspects of hepatic damage . . . . 124
Disorders of the liver and biliary tract . . . 129
Disorders of the exocrine pancreas . . . . 140
Disorders of the intestine . . . . . . . . . 142
Disorders of the peritoneum . . . . . . . 156
9. Pathology of the kidney and urinary
tract . . . . . . . . . . . . . . . . . . 159
Abnormalities of kidney structure . . . . . 159
Diseases of the glomerulus . . . . . . . . 161
Glomerular lesions in systemic disease . . . 168
Diseases of the tubules and interstitium . . 169
Diseases of the renal blood vessels . . . . 171
Neoplastic disease of the kidney. . . . . . 174
Disorders of the urinary tract . . . . . . . 175

10. Pathology of the endocrine system . . . . 179
Disorders of the pituitary . . . . . . . . . 179
Thyroid disorders. . . . . . . . . . . . . 183
Parathyroid disorders . . . . . . . . . . . 189
Disorders of the adrenal gland . . . . . . 191
Disorders of the endocrine pancreas . . . . 195
Multiple endocrine neoplasia
syndromes . . . . . . . . . . . . . . . 199
11. Pathology of the reproductive system . . . 201
Disorders of the vulva, vagina
and cervix . . . . . . . . . . . . . . . 201
Disorders of the uterus and
endometrium . . . . . . . . . . . . . . 204
Disorders of the ovary and fallopian tube. . 208
Disorders of the placenta and pregnancy. . 210
Disorders of the breast . . . . . . . . . . 214
Disorders of the penis . . . . . . . . . . 217
Disorders of the testis and epididymis . . . 217
Disorders of the prostate . . . . . . . . . 220
12. Pathology of the musculoskeletal system . 223
Disorders of bone structure . . . . . . . . 223
Infections and trauma . . . . . . . . . . 226
Tumours of the bones . . . . . . . . . . 228
Disorders of the neuromuscular junction . . 230
Myopathies . . . . . . . . . . . . . . . 231
Arthropathies . . . . . . . . . . . . . . 233
13. Pathology of the blood and immune
systems . . . . . . . . . . . . . . . . . 243
Autoimmune disease . . . . . . . . . . . 243
Amyloidosis . . . . . . . . . . . . . . . 250
Disorders of white blood cells . . . . . . . 251
Disorders of the spleen and thymus . . . . 261
Disorders of red blood cells . . . . . . . . 263
Disorders of haemostasis . . . . . . . . . 273
14. Pathology of the skin . . . . . . . . . . 279
Terminology of skin pathology . . . . . . 279
Inflammation and skin eruptions . . . . . 281
Infections and infestations . . . . . . . . 285
Disorders of specific skin structures . . . . 291
Disorders of pigmentation . . . . . . . . 294
Blistering disorders . . . . . . . . . . . . 296
Tumours of the skin . . . . . . . . . . . 298
Self-assessment . . . . . . . . . . . 305
Single best answer questions (SBAs) . . . . . 307
Extended-matching questions (EMQs). . . . . 315
SBA answers. . . . . . . . . . . . . . . . . 319
EMQ answers . . . . . . . . . . . . . . . . 325
Glossary . . . . . . . . . . . . . . . . . . . 327
Index . . . . . . . . . . . . . . . . . . . . 329

Crash Course Pathology ebook free download pdf

Crash Course Pathology ebook free download pdf

Crash Course Pathology ebook free download pdf

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